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P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. P-selectin, the largest selectin, is stored in α-granules of platelets and in Weibel–Palade bodies of endothelial cells, and is translocated to the cell surface of activated endothelial cells and platelets. E-selectin is not expressed under baseline conditions, except in skin microvessels, but is rapidly induced by inflammatory cytokines. P-selectin is an adhesion molecule expressed on activated platelets and endothelium.

P selectin

2019-07-12 · P-Selectin Antibody (CTB201) is a monoclonal anti-CD62 antibody that detects m, r, and h P-Selectin by WB, IP, IF, IHC(P) and FCM. Cited in 38 publications Search results for p-selectin at Sigma-Aldrich. Summary: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface. ELISA kits for the study of the target, P-Selectin are available in ready-to-use formats.

Artikelnummer: 636393 Produktnamn: Ms X Hu P Selectin

Select . in Hift .

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P-selectin glycoprotein ligand 1 (PSGL-1, CD162) and integrin αMβ2 ( Mac-1, CD11bCD18) are leukocyte P-selectin is a transmembrane protein present in the α granules of platelets and the Weibel-Palade bodies of endothelial cells. Following activation, Mayadas et.al confirmed that the combination of P-selectin and its ligand PSGL-1 mediates the adhesion of platelets to vascular endothelial cells and promotes P-Selectin Antibody (AK4) is a monoclonal anti-CD62 antibody that detects human P-Selectin by WB, IP, IF and FCM. Cited in 9 publications. Nov 16, 2017 P-selectin (CD62), a member of the selectin family, is confined to the α-granules of platelets and Weibel-Palade bodies of endothelial cells. P-selectin belongs to the family of selectin adhesion molecules, and is expressed by platelets and endothelial cells on stimulation.

Meaning of p-selectin. What does p-selectin mean?
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Kumar, Vinay, Abul K. Abbas, Dec 14, 2014 In this video we discuss the three different types of selectins and their P- Selectin and Pulmonary Arterial Thrombosis in Trauma and Disease P-Selektin. Synonyme: GRMP, CD62, LECAM3, PSEL, Selektin P, CD62P, GMP140 Englisch: P-selectin, selectin P P-selectin is a type-1 transmembrane protein that in humans is encoded by the SELP gene.P-selectin functions as a cell adhesion molecule (CAM) on the Selectin P ligand, also known as SELPLG or CD162 (cluster of differentiation 162 ), is a human gene.

Antigensymbol, P-Selectin. Antikroppstyp, Primary. Klonalitet, Monoclonal.
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2 days ago P-selectin is a type-1 transmembrane protein that in humans is encoded by the SELP gene. [5] P-selectin functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets .

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We investigated the role of platele … P-selectin is a cell adhesion molecule of platelets and endothelial cells stored in secretory granules and rapidly expressed on the plasma membrane on activation.10-13 After expression on the cell surface both endothelial and platelet P-selectin mediate leukocyte adhesion.14 Whereas endothelial P-selectin has clearly been shown to be involved P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. Definition of p-selectin in the Definitions.net dictionary. Meaning of p-selectin. What does p-selectin mean? Information and translations of p-selectin in the most comprehensive dictionary definitions resource on the web. P-selectin is a cell adhesion molecule of platelets and endothelial cells stored in secretory granules and rapidly expressed on the plasma membrane on activation.10-13 After expression on the cell surface both endothelial and platelet P-selectin mediate leukocyte adhesion.14 Whereas endothelial P-selectin has clearly been shown to be involved This tight link is partly attributable to P-selectin, which is functional not only when expressed on the surface of activated platelets and endothelial cells, but also when shed, generating its soluble form, termed sP-selectin.

Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells.